Publications

GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

Ilon Liu*, Gustavo Alencastro Veiga Cruzeiro*, Lynn Bjerke*, Rebecca F Rogers*, Yura Grabovska, Alexander Beck, Alan Mackay, Tara Barron ... Johannes Gojo, Michelle Monje, Chris Jones*, Mariella G Filbin*

Cancer Cell · 2024 · doi:10.1016/j.ccell.2024.08.006

Featured in the Harvard Brain Science Initiative.

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

Ilon Liu*#, Li Jiang*, Erik R Samuelsson*, Sergio Marco Salas, Alexander Beck, Olivia A Hack, Daeun Jeong, ... Michelle Monje*, Mats Nilsson*, Mariella G Filbin*#

Nature Genetics · 2022 · doi:10.1038/s41588-022-01236-3​

Featured in Nature Genetics News & Views.

Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions

Alexander Beck*, Lisa Gabler-Pamer*, Gustavo Alencastro Veiga Cruzeiro, Sander Lambo, Bernhard Englinger, McKenzie L Shaw, Olivia A Hack, Ilon Liu, ... Marcel Kool*, Volker Hovestadt*, Mariella G Filbin*

Nature Cancer · 2025 · doi:10.1038/s43018-025-00964-9

Epidemiology of WHO grade 2 and grade 3 gliomas from 2009 to 2021 in Germany

Daniel Weidl, David Capper, Julia Onken, Ilon Liu, Doris Glaser, Felix Orben, Karolin Eberle, Jan Coburger, Lars Bullinger

Journal of Neuro-Oncology · 2025 · doi:10.1007/s11060-025-05068-z

Dissecting the immune landscape in pediatric high-grade glioma reveals cell state changes under therapeutic pressure

Jenna LaBelle*, Rebecca D Haase*, Alexander Beck, Jacob Haase, Li Jiang, Carlos Alberto Oliveira de Biagi Jr, Sina Neyazi, Bernhard Englinger, Ilon Liu ... Kai W Wucherpfennig*, Mariella G Filbin

Cell Reports Medicine · 2025 · doi:10.1016/j.xcrm.2025.102095

VGLL fusions define a new class of intraparenchymal central nervous system schwannoma

Simone Schmid, Kanish Mirchia, Anna Tietze, Ilon Liu, Christin Siewert, Jakob Nückles, Jens Schittenhelm ... David TW Jones, David Capper

Neuro-Oncology · 2025 · doi:10.1093/neuonc/noae269

GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

Ilon Liu*, Gustavo Alencastro Veiga Cruzeiro*, Lynn Bjerke*, Rebecca F Rogers*, Yura Grabovska, Alexander Beck, Alan Mackay, Tara Barron ... Johannes Gojo, Michelle Monje, Chris Jones*, Mariella G Filbin*

Cancer Cell · 2024 · doi:10.1016/j.ccell.2024.08.006

Featured by the Harvard Brain Science Initiative.

Diffuse midline glioma invasion and metastasis rely on cell-autonomous signaling

Marco Bruschi, Lilia Midjek, Yassine Ajlil, Stephanie Vairy, Manon Lancien, Samia Ghermaoui, Thomas Kergrohen, Maite Verreault, Ahmed Idbaih, Carlos Alberto Oliveira de Biagi Junior, Ilon Liu, Mariella G Filbin ...Marie-Anne Debily, David Castel

Neuro-Oncology · 2024 · doi:10.1093/neuonc/noad161

Characterizing the biology of primary brain tumors and their microenvironment via single-cell profiling methods

L Nicolas Gonzalez Castro*, Ilon Liu*, Mariella G Filbin

Neuro-Oncology · 2023 · doi:10.1093/neuonc/noac211

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

Ilon Liu*#, Li Jiang*, Erik R Samuelsson*, Sergio Marco Salas, Alexander Beck, Olivia A Hack, Daeun Jeong, ... Michelle Monje*, Mats Nilsson*, Mariella G Filbin*#

Nature Genetics · 2022 · doi:10.1038/s41588-022-01236-3​

Featured in Nature Genetics News & Views.

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Eshini Panditharatna*, Joana G Marques*, Tingjian Wang, Maria C Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves ... Mariella G Filbin

Cancer Discovery · 2022 · doi:10.1158/2159-8290.CD-21-1491

The imitation game: How glioblastoma outmaneuvers immune attack

Ilon Liu, Olivia A Hack, Mariella G Filbin

Cell · 2021 · doi:10.1016/j.cell.2021.04.008

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

Johannes Gojo*, Bernhard Englinger*, Li Jiang*, Jens M Hübner, McKenzie L Shaw, Olivia A Hack, Sibylle Madlener, Dominik Kirchhofer, Ilon Liu ... Mariella G Filbin

Cancer Cell · 2020 · 10.1016/j.ccell.2020.06.004

Catalytic properties, localization, and in vivo role of Px IV, a novel tryparedoxin peroxidase of Trypanosoma brucei

Ilon Liu, Marta Bogacz, Corinna Schaffroth, Natalie Dirdjaja, R Luise Krauth-Siegel

Molecular and Biochemical Parasitology · 2016 · doi:10.1016/j.molbiopara.2016.05.013

IL-1α reversibly inhibits skeletal muscle ryanodine receptor. a novel mechanism for critical illness myopathy?

Oliver Friedrich, Bing Yi, Joshua N Edwards, Barbara Reischl, Anette Wirth-Hücking, Andreas Buttgereit, Roland Lang, Cornelia Weber, Fabian Polyak, Ilon Liu, Frederic von Wegner, Tanya R Cully, Aven Lee, Patrick Most, Mirko Völkers

American Journal of Respiratory Cell and Molecular Biology · 2014 · doi:10.1165/rcmb.2013-0059OC